Anti-Aging Pyrroloquinoline Quinone PQQ powder

Natural Nutritional Supplement Of Methoxatin(PQQ)

Pyrroloquinoline quinone, English name methoxatin, molecular formula is C14H6N2O8, molecular weight is 330.206, CAS registration number is 72909-34-3, a chemical intermediate.

Brief Introduction

PQQ is widely present in a variety of common foods such as fruits, vegetables, cereals and beverages, including plant foods and animal foods, and its concentration ranges from 3.65-61.0 ng/g or ng/mL. The total content of PQQ and its derivative IPQ in human milk is 140-180 ng/mL. It is suggested that it may play a very important role in the growth and development of newborn infants.

Benefits Of PQQ

1.super antioxidant ability and Boosting Immunity Extract

PQQ has a strong ability to remove peroxides, and can effectively remove HO• and O2• -, which is reflected in: protecting mitochondria from oxidative damage; Inhibition of lipid peroxides; Protect heart muscle cells from ischemia and reperfusion damage; Protect the REDOX sites of NMDA receptors, promote the recovery of spinal cord injury, prevent cerebral ischemia and hypoxia, and avoid severe shock in animal models; At the same time, PQQ can also protect the heart against myocardial ischemia and myocardial infarction, and these protective effects are due to the antioxidant capacity of PQQ.

2.Liver protection and Improved Digestion Extract

PQQ can protect the liver against liver damage induced by alcohol and carbon tetrachloride and liver fibrosis induced by TAA.

3.Neuroprotective effect and  Improving Vision Extract

PQQ can improve the neuronal damage caused by oxygen and sugar deprivation model, reduce the change of nidellite content caused by D-galactose treatment, inhibit neuronal degeneration, weaken the neuronal damage caused by amyloid beta, and help promote the secretion of neurotrophic factors. In addition, PQQ can also significantly improve the memory function of rats, and has obvious effects on memory retention and dementia prevention.

4.Improved reproductive performance and Weight Loss Extract

The diet deprived of PQQ was given to newborn female rats. The results showed that if the diet of female rats lacked PQQ, it was manifested as reproductive disorder. After breeding and giving birth, the newborn rats would show symptoms such as growth retardation and stunting, and the female rats would also show infertility or eat the newborn rats. If the appropriate amount of PQQ is added at this time, the growth of the young mice, the fertility and behavior of the female mice are all equal, and the growth of the young mice gradually becomes normal. Under the condition of feeding sufficient PQQ, the reproductive ability and litter size of the female mice were significantly higher than that of the control group.

5.Growth factor-like effects and Sleeping Aid Extract

Diet deprivation of PQQ in maternal female rats can cause growth retardation and stunting in newborn pups. The lack of PQQ in diet can also lead to a large decrease in the content of lysine oxidase in the skin of rats, resulting in reduced skin collagen content and elastic protein cross-linking damage, which is manifested as fragile and flaking skin, thinning hair, bending of the body, and severe abdominal bleeding or even death. Therefore, PQQ is an essential nutrient factor for animal growth and development. In addition, PQQ was also found in human milk, suggesting that PQQ plays a very important role in the growth and development of young animals.

6.Anti-inflammatory function, enhance the body's immune regulation.

PQQ can clear ROS and fight inflammatory damage caused by oxidative stress. Injection of PQQ before carrageene-induced mouse paw inflammation decreased. When PQQ was lacking in the diet, the content of interleukin 2 in mice was significantly reduced, while when PQQ was added, the spleen cells had A better response to mitogen A and lipopolysaccharide. The addition of PQQ in parenteral nutrition increased the number of lymphocytes in lymphocyte aggregation, as well as CD4+ and CD8+ cells in lymphocyte aggregation. And it can restore the integrity of the lymphatic organs associated with the gut to a certain extent.